using pseudoephedrine for weight loss may not be recommended by your doctor, but it is an increasingly popular way of increasing your metabolism. Pseudoephedrine is an ingredient found in many decongestants, both over-the-counter and prescription. The active ingredient pseudoephedrine HCL is a stimulant that is able to relieve symptoms of sinus congestion and pressure in the sinus cavity. In addition to treating cold symptoms, it is used by asthma patients with difficulty berating as well as by individuals with allergies. Because it is a central nervous system stimulant, it does present certain weight loss benefits such as appetite suppression and increased metabolism.
Pseudoephedrine is one of two alkaloids from the ephedra sinica herb that are known to burn fat and cause weight loss. The other ephedra extract is ephedrine which has become one of the most popular diet pills in North America. While the FDA has banned ephedra as a component of weight loss supplements, ephedrine is still available legally if purchased as a decongestant or hay fever remedy.
Both ephedrine and pseudoephedrine work by opening the blood vessels and nasal passages in the body. This effect, known as vasodilation, results in an increase in the heart rate and blood pressure leading to an increase in metabolism. According to a study reported in the British Journal of Clinical Pharmacology, taking pseudoephedrine for weight loss can increase athletic performance for competitive athletes.
A team of researchers from Australia and New Zealand ran a clinical study involving 22 male athletes who were given 180 mg of pseudoephedrine 45 minutes before a workout. Their performance was then recorded in a number of muscle-strengthening activities. One exercise in particular involving knee extensions showed that the athletes achieved a greater range of motion after taking pseudoephedrine. They also achieved greater maximum cardiovascular output in a cycling test and showed increased lung capacity. These powerful effects of pseudoephedrine make it effective for promoting weight loss.
But before you take pseudoephedrine to reach your goal weight, it is important to be aware of possible side effects and to know how to prevent them. You may experience headaches, nervousness, difficulty sleeping, or nausea when taking pseudoephedrine. If consuming larger than recommended doses, you could experience chest pain or heart complications such as palpitations and high blood pressure. It is best to take pseudoephedrine in cycles and not for long durations of time, and if you have outstanding medical conditions make sure to consult with your doctor before you begin using pseudoephedrine hcl.
Ephedrine vs. Pseudoephedrine for Weight Loss:
If you are looking to achieve more significant weight loss results, some people use Ephedrine HCL instead of Pseudoephedrine. Ephedrine and Pseudoephedrine are both considered Symphatomimetic drugs, though there are some important differences between the two. Scientifically, ephedrine and Pseudoephedrine have different chemical structures found in their molecular hydroxyl branch. What that means is that ephedrine is typically used to increase the circulation in the body and promote thermogenesis while pseudoephedrine is used most effectively to decongest nasal passages. Pure ephedrine contains a stronger version of the stimulant that will cause your body to release more adrenalin, resulting in an increase metabolic rate and greater average monthly weight loss.
- The apparent absence of serotonin-mediated vascular thermogenesis in perfused rat hindlimb may result from vascular shunting
- January B, et al. beta2-adrenergic receptor desensitization, internalization, and phosphorylation in response to full and partial agonists. J Biol Chem. (1997)
- Kenakin TP. Cellular assays as portals to seven-transmembrane receptor-based drug discovery. Nat Rev Drug Discov. (2009)
- Effects of a weight-loss aid in healthy overweight adults: double-blind, placebo-controlled clinical trial