Ephedrine is a powerful and effective diet and weight loss supplement that is most commonly marketed in either hydrochloride or sulfate form. In scientific terms, a hydrochloride is a salt that is formed with hydrochloric acid while a sulfate is a salt made from sulfuric acid. This simple difference in the chemical structure means that ephedrine sulfate and ephedrine hydrochloride (shorted as ephedrine HCL) produce very different weight loss effects. In this article, we will compare the effects and side effects of Ephedrine Sulfate vs. Ephedrine HCL.
Ephedrine is a chemical alkaloid that comes from the Ma Huang or Ephedra Sinica Plant in the Ephedraceae genus. It is known as a sympathomimetic drug because it can imitate the effect that adrenalin and norepinephrine have on the body. As a vasolidator, it increases the circulation and improves the ability of blood and oxygen to get into the muscle tissues. This makes it an effective treatment of low blood pressure as it stimulates the central nervous system. It also helps improve physical strength and athletic performance by boosting the cardiovascular system.
Ephedrine is an effective appetite suppressant as well. This means that individuals on ephedrine are more likely to be able to stick to a 2000 calorie or less diet, thus creating a calorie deficiency for weight loss. In addition to this, it boosts the metabolism allowing the body to burn more calories and fat through the day through what is known as non-exercise activity thermogenesis. Most dieters will take this drug in the morning or early afternoon to get the best possible metabolic boost effect throughout the day. Athletes may also use the drug as it increases energy levels and improves the ability to exercise for longer durations in your target heart rate zone. The supplement is also known to help you lose weight without causing any loss in muscle mass by targeting fat.
Many people looking for readily accessible and cheap ephedrine will purchase a nasal decongestant or bronchodilator such as Bronkaid tablets to get their dosage of the drug. This drug contains ephedrine sulfate and is available without a prescription in the United States. However, it is illegal to market Ephedrine as a weight-loss product in most countries around the world so it must be packaged and sold as a hayfever treatment.
When looking at the effectiveness of a particular ephedrine product for weight loss, it is important to consider foremost the amount of ephedrine alkaloid present in the product. This is the active ingredient that causes the body’s metabolism to increase which leads to fat being burned.
According to recent scientific analyses, Ephedrine sulfate contains approximately 77% approximately 77% pure ephedrine alkaloid by weight. Therefore, a 25 mg dose of ephedrine sulfate would equal 19.25 mg of active ephedrine.
Ephedrine is much more widely available in synthesized hydrochloride format as Ephedrine HCL. Brands such as Kaizen Ephedrine, Vasopro Ephedrine, and Synergenex Ephedrine are some of the most popular forms of Ephedrine HCL. Like Ephedrine Sulfate, it is available over the counter in the United States, though the sale is regulated by certain restrictions in different states. Ephedrine HCL also must be marketed as a bronchodilator or asthma treatment in order to be sold legally.
Like Ephedrine Sulfate, we must look at the quantity of active ingredient in Ephedrine HCL to determine how effective this drug is for weight loss. Ephedrine HCL is approximately 82% ephedrine by weight. That means that 25 mg ephedrine hydrochloride equals 20.5 mg ephedrine alkaloid. This is .75 mg more Ephedrine than what is provided with Ephedrine Sulfate. Thus, we can conclude that Ephedrine HCL is a more powerful weight loss supplement than Ephedrine Sulfate.
- Astrup A, et al. Enhanced thermogenic responsiveness during chronic ephedrine treatment in man. Am J Clin Nutr. (1985)
- Astrup A, et al. Pharmacology of thermogenic drugs. Am J Clin Nutr. (1992)
- The desensitization and resensitization patterns of quiescent A431 cells induced by epinephrine is sensitive to stimulation duration and several inhibitors